Labs and facilities
Transactiva has the working spaces and the equipment suitable to perform the development of the technological platform for drug production in a plant, eg, from gene design to the supply of biomass amounts sufficient to support clinical trials in Phase I/II.
Expression vectors are prepared in molecular biology labs covering an area of 150 m2, equipped with all instruments needed for cloning and sub-cloning of DNA sequences.
Plant transformation and regeneration is carried out in an in-vitro culture facility including climatic chambers (50 m2). Until the selection of the productive line, GM plants are grown within rooms endowed with NFT-hydroponic systems (50 m2) or in a small greenhouse (120 m2); in subsequent stages, when Master- and Working Seed Banks have to be established or elite lines are expanded for yielding purposes, larger greenhouses (approx. 2,750 m2) are used.
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The selection of productive lines and the development of extraction/purification protocols of therapeutic proteins are performed in a biochemical lab (100 m2) with equipment validated for drug production.
In addition, Transactiva has a technical area (50 m2) where processing of GM rice seed and packaging can be done with equipment specifically designed to warrant high quality standards.